age well

Menopause treatment in downtown Naples

You’ve been told it’s normal. We think you deserve better.

There’s a quiet frustration that builds when nothing seems to work. Diet after diet, effort without results, and doctors who dismiss your symptoms as just “getting older.” You’re not imagining it—and you’re not the only one. At RegenCen Naples, we help patients reclaim clarity, strength, and a healthy weight through medically guided care. Semaglutide is just one part of the story. The real power lies in knowing what’s going on and having a plan that fits you.

Our mission at RegenCen in Downtown Naples

Aging well isn’t about accepting less. It’s about knowing more.

Most clinics focus on what they offer. We start with why we offer it. At RegenCen, we believe aging is natural — but struggling through it shouldn’t be.

Our downtown Naples location is part of a physician-led practice built on trust, not trends. We listen first. We educate. Then we guide you toward care that makes medical sense for where you are in life. Whether it’s hormone shifts, unexplained weight gain, or a fog that’s settled over your days — we’re here with real answers and real treatment options.

HOW TO FIND US IN DOWNTOWN NAPLES

hours, map & location information

Hours
Monday: 8 AM – 5 PM
Tuesday: 8 AM – 5 PM
Wednesday: 9 AM – 5 PM
Thursday: 8 AM – 5 PM
Friday: 8 AM – 1 PM
Saturday & Sunday: Closed

Looking for menopause treatment or hormone therapy near 5th Avenue South or Old Naples?

We're conveniently located at 700 2nd Ave N, Suite 205, Naples, FL 34102 and provide a comprehensive suite of wellness services tailored to your needs.

Our RegenCen clinic is situated just blocks from Cambier Park and the restaurants and shops of 5th Avenue South, making it one of the most centrally located hormone and longevity clinics in Naples. Patients often stop in after a morning at Naples Pier or a walk through downtown—our discreet, second-floor location provides easy access and professional care in a calm, private setting.

We serve patients from across Old Naples, Aqualane Shores, and Coquina Sands—neighborhoods known for their commitment to wellness, vitality, and a long-term approach to aging. Whether you're a full-time resident or a seasonal visitor, RegenCen offers physician-led semaglutide treatment, hormone support, and personalized midlife care designed for your lifestyle.

Our care extends beyond the city center too. Patients from Royal Harbor, East Naples, and even Lely Resort choose RegenCen for medically guided solutions to symptoms like fatigue, stubborn weight gain, low libido, and brain fog. If you're searching for a clinic near you that combines medical expertise with personalized attention, you'll find it here—right in the heart of downtown Naples.

For directions, click the map or call/text us at 239-367-7353.

Your Downtown Naples Wellness & Hormone Care Team

Keya Patel, PA-C Sarasota RegenCen Provider
Angela Zunzunegui
Danielle Santos, PA-C
Gustav-Lo-MD-Founder

Keya Patel, PA-C

Angela Zunzunegui, PA-C

Danielle Santos, PA-C

Gustav Lo, MD

What we offer in downtown naples

Your symptoms have been trying to tell you something. We speak that language.

The mood swings, the disrupted sleep, the weight that won’t respond the way it used to — these aren’t random. They’re hormonal. At RegenCen Naples, we help women navigate menopause and perimenopause with a science-backed, physician-led approach. Our care is individualized, lab-guided, and built for your long-term wellness — not a formula.

Hormone shifts can feel invisible. The right care shouldn’t be.

When your labs are “normal” but you feel anything but, it’s easy to wonder if you’re just imagining things. You’re not. At RegenCen Naples, we take your symptoms seriously. RegenHRT, our approach to hormone replacement therapy is highly individualized and our providers take time to understand what’s going on beneath the surface—and help you find a plan that works, not just one that looks good on paper.

Wellness Consultations

At RegenCen, our wellness consultations are the first step in helping you feel and perform your best. During this one-on-one visit, we take the time to understand your goals, health history, and symptoms. Whether you’re struggling with low energy, weight changes, brain fog, or hormone shifts, your provider will build a personalized plan that may include advanced testing, nutrition support, hormone optimization, or regenerative therapies. Patients leave with a clear path forward — no guessing, just a medically guided plan designed around your needs.

Optimizing how you age isn’t about chasing youth—it’s about protecting the life you love. RegenCen offers longevity-focused care that starts with deep lab testing and a full-body review of hormone levels, inflammation, and energy systems. From there, we tailor a regenerative plan that may include NAD+ for cellular support, bioidentical hormones for balance, and PRF for tissue and joint repair. The result? Fewer aches, clearer thinking, better movement—and a longer, healthier life.

Offered at our downtown Naples clinic, conveniently serving patients from Bonita Springs, Fort Myers, and Estero. Our Naples team has helped thousands of men and women regain energy, balance, and confidence through tailored wellness care.

More about Naples Wellness Consultations 

RegenHRT ™ — Hormone Therapy

At RegenCen, hormone therapy is guided by the RegenHRT approach, our physician-directed method for restoring and maintaining balanced hormone levels over time. Treatment begins with a comprehensive evaluation of symptoms, medical history, and lab testing. From there, care is tailored to each patient through personalized dosing, regular monitoring, and thoughtful adjustments as the body changes. The goal is simple. Help patients feel stronger, clearer, and more balanced while supporting long-term health.

Menopause treatments
Menopause can bring significant changes in sleep, mood, metabolism, and overall well-being. Through the RegenHRT approach, our providers develop individualized treatment plans designed to restore hormonal balance and relieve common symptoms such as hot flashes, insomnia, mood changes, and low libido. Care is guided by both symptoms and lab testing to ensure treatment remains effective over time.
Learn more about menopause treatment 

Perimenopause treatments
Hormonal changes often begin years before menopause. During perimenopause, fluctuating estrogen and progesterone levels can lead to fatigue, brain fog, sleep disruption, anxiety, and weight changes. RegenCen specializes in identifying these early hormonal shifts and providing thoughtful hormone therapy that evolves as the body changes.
Learn more about perimenopause treatment 

Testosterone treatments
Testosterone plays an important role in energy, muscle strength, focus, and overall vitality for men. When levels decline, many men experience fatigue, reduced motivation, weight gain, and changes in libido. RegenCen provides physician-guided testosterone therapy designed to restore levels to a healthy physiologic range while monitoring long-term health and treatment response. We also offer ED treatments for men looking to address both concerns under one roof.
Learn more about testosterone treatment 

Vaginal Rejuvenation

Vaginal rejuvenation is also known as “feminine rejuvenation” and is defined by the American Board of Cosmetic Surgery as one or more “procedures used to reduce, reshape, or tighten female genital tissues to restore a firmer tone and a more youthful and symmetrical appearance.” Feminine rejuvenation can also alleviate problems caused by vaginal tissue laxity. At RegenCen, we offer advanced, evidence-based vaginal rejuvenation treatments such as women's sexual health, FormaV, PRF Vaginal Rejuvenation, VTone, and MorpheusV

Depending on the treatment, feminine rejuvenation can:

  • Improve vaginal tone and elasticity
  • Treat dyspareunia (painful intercourse)
  • Reduce or eliminate urinary incontinence (loss of bladder control)
  • Relieve vaginal itching, burning, pain or dryness

More about advanced Vaginal Rejuvenation Treatments in downtown Naples 

Medical Weight Loss
At RegenCen, weight loss is approached as a medical and metabolic process, not a matter of willpower. As hormones and metabolism change over time, many patients find that traditional diet and exercise no longer produce the same results. Our Naples weight loss clinic focuses on understanding why, then building a plan that restores balance and supports how your body regulates energy, appetite, and fat storage.
 
Every program begins with a comprehensive consultation. We evaluate your goals, medical history, and key metabolic factors to create a personalized strategy designed for sustainable, long-term results.
 
Treatment may include physician-guided GLP-1 weight loss injections such as semaglutide or tirzepatide, selected based on how your body responds to treatment. These medications can help regulate appetite, improve insulin sensitivity, and support more consistent progress. For some patients, we incorporate additional therapies such as NAD+ to support cellular energy and recovery, or targeted metabolic support like B-Fit+.
 
Care is closely monitored and adjusted over time to ensure progress remains steady and aligned with your goals. Many patients notice improvements beyond the scale, including better energy, fewer cravings, and a more stable, sustainable approach to maintaining results.
 
At RegenCen, the goal is not short-term weight loss. It is helping you achieve measurable, lasting change with a plan built around your physiology and guided by clinical expertise.
 

More about Medical Weight Loss & Semaglutide in downtown Naples 

NAD+ IV Therapy & Infusions

You don’t have to feel burned out to want more energy. NAD+ IV therapy is one of the simplest ways to recharge your system at the cellular level - helping you think clearer, sleep better, and recover faster. At RegenCen, we offer NAD+ infusions in Naples in a calm, professional setting, so you can relax while your body repairs, restores, and reboots. Whether you’re worn down or just want to stay ahead, this is a game-changer.

In addition to NAD+, we also offer IV Therapy, Myers Cocktail & Vitamin Drips at RegenCen. Struggling to recover from an illness? Looking for a quick way to boost energy and performance before an event or demanding physical activity? You can feel better in an hour! We treat symptoms from pain to fatigue to overall wellness. 

More about Naples, FL NAD IVs and IMs 

PRF Musculoskeletal Injections

Platelet-Rich Fibrin (PRF) musculoskeletal injections use your body’s own healing factors to target joint pain, arthritis, tendonitis, and soft tissue damage. Unlike cortisone shots that only mask pain, PRF supports true repair by stimulating natural healing at the source. Treatments are performed in-office with little downtime, making them a safe, drug-free alternative for patients looking to avoid surgery or long-term medications.

In Naples, patients often choose PRF to avoid joint replacement or repetitive steroid injections. Whether you’re an active adult, an athlete, or just tired of daily aches, PRF offers lasting relief.

More about Naples PRF Musculoskeletal Injections 

Thinning Hair Treatments

Hair loss doesn’t just affect appearance - it affects confidence. At RegenCen, we treat thinning hair with advanced, non-surgical therapies designed to restore both density and self-assurance. Options may include platelet-rich fibrin (PRF) scalp injections, prescription medications, or supportive wellness treatments that address underlying hormone or nutrient imbalances. With a customized plan, many patients see thicker, healthier hair and renewed confidence without transplants or surgery.

Available at our Naples location, serving men and women throughout Bonita Springs, Estero, Marco Island, and Aqualane Shores. Our Naples providers specialize in natural, minimally invasive approaches to restore hair growth.

More about Naples Treatments to Grow Thinning Hair 

Peptides

We offer personalized peptide therapy, Sermorelin therapy, GLP-1 weight loss support, PRP, and other regenerative treatments to help support energy, body composition, recovery, metabolic health, and healthy aging.

At RegenCen, your care is guided by a licensed medical provider and tailored to your symptoms, health history, lab work, and goals. All therapies are reviewed for medical appropriateness and provided under clinical oversight in accordance with applicable state and federal requirements.

Menopause Society Certified Practitioners in Naples, FL, serving surrounding Old Naples, Aqualane Shores, Coquina Sands, and more

Menopause Society Certified Practitioners in Naples, FL, serving surrounding Old Naples, Aqualane Shores, Coquina Sands, and more

Menopause Society Certified Practitioners at RegenCen MD.
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4.9

★★★★★
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Physician-led hormone care in the heart of downtown Naples

Physician-led hormone care in the heart of downtown Naples

Our clinic is located at 700 2nd Ave N, Suite 205—steps from Naples Community Hospital and walkable from Cambier Park. Whether you’re coming from Old Naples, Port Royal, or the Moorings, our space is private, easy to find, and rooted in personalized medical care.

We’re located behind Wynn’s Market in the Lakeview Medical Building. Take the elevator to the second floor, Suite 205.

Meet your providers

Dr. Gus Lo, Chief Medical Officer

Meet Dr. Gus Lo — the physician behind our care standards. With more than 30 years of clinical experience and medical leadership, Dr. Gustav Lo trains and leads RegenCen's team of providers who specialize in bioidentical hormone replacement, medical weight loss, and longevity.

Read full bio.

Angela Zunzunegui, PA-C

Angela Zunzunegui, PA-C helps women in Southwest Florida feel strong, balanced, and in control through every stage of midlife. With expertise in hormone therapy and medical weight loss, she offers personalized care that supports real, lasting change.

Read full bio.

Danielle Santos, PA-C

Danielle Santos, PA-C helps patients feel like themselves again with personalized hormone therapy and sustainable weight loss care. Known for her warmth and clinical precision, she creates thoughtful plans that restore energy, balance, and long-term confidence.



Read full bio.

Keya Patel, PA-C

Keya Patel, PA-C helps patients feel balanced, energized, and confident with personalized hormone therapy and weight loss care. With a calm, thoughtful approach, she blends medical expertise and real-world support to deliver lasting, meaningful change.

Read full bio.

RegenCen Naples

naples HRT

Hormone replacement therapy in Naples
that meets you where you are

Let’s be honest—hormone therapy can feel overwhelming. Is it safe? Do I really need it? How do I know what’s “normal”? These are questions we hear every day, and they deserve thoughtful, clinical answers. At RegenCen, hormone replacement therapy isn’t a blanket solution. It’s a tool we use when symptoms like sleep disruption, mood changes, or energy loss start interfering with your quality of life.

Every patient begins with lab work, followed by a consult with one of our medical providers. Together, we look at your hormone profile, your symptoms, and your goals—then decide, together, what makes sense for you.

Frequently Asked Questions
about RegenCen Naples Downtown

Is menopause treatment available near me in downtown Naples?
How does semaglutide help with weight loss?
Is semaglutide right for me?
Do I have to follow a strict diet with semaglutide?
What are common symptoms of hormone imbalance?
What types of hormone therapy do you offer?
Is your downtown Naples location accepting new patients?
How is RegenCen different from a weight loss clinic?
Can I combine hormone therapy with semaglutide?
Do you see patients from nearby cities outside Naples?

You’ve managed long enough. Let’s build a plan that actually works.

If your symptoms have been dismissed, or you’ve been quietly managing them on your own, this is your sign to get a real answer.

At RegenCen downtown Naples, we offer physician-led care for menopause, hormone health, and everything that comes with midlife. Weight. Fatigue. Brain fog. Mood. It’s all connected, and it’s all worth treating. Use the form here to get in touch. We’ll reach out to schedule a no-pressure consultation.